CharlesDexterWard'swifeenliststhehelpofaprivatedetectivetofindoutwhatherhusbandisuptoinaremotecabinownedbyhisfamilyforcenturies.The  dd
husbandisachemicalengineer|andthesmellsfromhisexperiments(andthedeliveryofwhatappeartobehumanremainsatallhours)arebeginningtoarousethe
attentionofneighborsandlocallawenforcementofficials.Whenthedetectiveandwifefindadiaryofthehusband'sancestorfrom1771|andreportsofgruesome
murdersintheareabegintosurface|theybegintosuspectthatsomeveryunnaturalexperimentsarebeingconductedintheoldhouse.BasedonanH.P.Lovecraft
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